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The First Transmembrane Domain of Lipid Phosphatase SAC1 Promotes Golgi Localization
The lipid phosphatase Sac1 cycles between endoplasmic reticulum and cisternal Golgi compartments. In proliferating mammalian cells, a canonical dilysine motif at the C-terminus of Sac1 is required for coatomer complex-I (COP-I)-binding and continuous retrieval to the ER. Starvation triggers accumula...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731292/ https://www.ncbi.nlm.nih.gov/pubmed/23936490 http://dx.doi.org/10.1371/journal.pone.0071112 |