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Production and Characterization of Novel Recombinant Adeno-Associated Virus Replicative-Form Genomes: A Eukaryotic Source of DNA for Gene Transfer

Conventional non-viral gene transfer uses bacterial plasmid DNA containing antibiotic resistance genes, cis-acting bacterial sequence elements, and prokaryotic methylation patterns that may adversely affect transgene expression and vector stability in vivo. Here, we describe novel replicative forms...

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Detalles Bibliográficos
Autores principales: Li, Lina, Dimitriadis, Emilios K., Yang, Yu, Li, Juan, Yuan, Zhenhua, Qiao, Chunping, Beley, Cyriaque, Smith, Richard H., Garcia, Luis, Kotin, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731302/
https://www.ncbi.nlm.nih.gov/pubmed/23936358
http://dx.doi.org/10.1371/journal.pone.0069879