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WT1 Promotes Cell Proliferation in Non-Small Cell Lung Cancer Cell Lines through Up-Regulating Cyclin D1 and p-pRb In Vitro and In Vivo

The Wilms’ tumor suppressor gene (WT1) has been identified as an oncogene in many malignant diseases such as leukaemia, breast cancer, mesothelioma and lung cancer. However, the role of WT1 in non-small-cell lung cancer (NSCLC) carcinogenesis remains unclear. In this study, we compared WT1 mRNA leve...

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Detalles Bibliográficos
Autores principales: Xu, Caihua, Wu, Chen, Xia, Yang, Zhong, Zhaopeng, Liu, Xiang, Xu, Jing, Cui, Fei, Chen, Bin, Røe, Oluf Dimitri, Li, Aihong, Chen, Yijiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731304/
https://www.ncbi.nlm.nih.gov/pubmed/23936312
http://dx.doi.org/10.1371/journal.pone.0068837