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A Rational Diagnostic Algorithm for the Identification of ALK Rearrangement in Lung Cancer: A Comprehensive Study of Surgically Treated Japanese Patients

BACKGROUND: EML4-ALK fusion gene is found in only a small subset (2–6%) of non-small cell lung cancer. There is an urgent need to establish a rational diagnostic algorithm to identify this rare but important fusion in lung cancer. METHODS: We performed a comprehensive analysis of EGFR/KRAS mutation...

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Detalles Bibliográficos
Autores principales: Takamochi, Kazuya, Takeuchi, Kengo, Hayashi, Takuo, Oh, Shiaki, Suzuki, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731315/
https://www.ncbi.nlm.nih.gov/pubmed/23936355
http://dx.doi.org/10.1371/journal.pone.0069794