Serum TRPM1 Autoantibodies from Melanoma Associated Retinopathy Patients Enter Retinal ON-Bipolar Cells and Attenuate the Electroretinogram in Mice

Melanoma-associated retinopathy (MAR) is a paraneoplastic syndrome associated with cutaneous malignant melanoma and the presence of autoantibodies that label neurons in the inner retina. The visual symptoms and electroretinogram (ERG) phenotype characteristic of MAR resemble the congenital visual di...

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Detalles Bibliográficos
Autores principales: Xiong, Wei-Hong, Duvoisin, Robert M., Adamus, Grazyna, Jeffrey, Brett G., Gellman, Celia, Morgans, Catherine W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731326/
https://www.ncbi.nlm.nih.gov/pubmed/23936334
http://dx.doi.org/10.1371/journal.pone.0069506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731326/
https://www.ncbi.nlm.nih.gov/pubmed/23936334
http://dx.doi.org/10.1371/journal.pone.0069506

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