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Influence of Macrocyclic Chelators on the Targeting Properties of (68)Ga-Labeled Synthetic Affibody Molecules: Comparison with (111)In-Labeled Counterparts

Affibody molecules are a class of small (7 kDa) non-immunoglobulin scaffold-based affinity proteins, which have demonstrated substantial potential as probes for radionuclide molecular imaging. The use of positron emission tomography (PET) would further increase the resolution and quantification accu...

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Detalles Bibliográficos
Autores principales: Strand, Joanna, Honarvar, Hadis, Perols, Anna, Orlova, Anna, Selvaraju, Ram Kumar, Karlström, Amelie Eriksson, Tolmachev, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731330/
https://www.ncbi.nlm.nih.gov/pubmed/23936372
http://dx.doi.org/10.1371/journal.pone.0070028