Distinct Mechanisms for Induction and Tolerance Regulate the Immediate Early Genes Encoding Interleukin 1β and Tumor Necrosis Factor α

Interleukin-1β and Tumor Necrosis Factor α play related, but distinct, roles in immunity and disease. Our study revealed major mechanistic distinctions in the Toll-like receptor (TLR) signaling-dependent induction for the rapidly expressed genes (IL1B and TNF) coding for these two cytokines. Prior t...

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Detalles Bibliográficos
Autores principales: Adamik, Juraj, Wang, Kent Z. Q., Unlu, Sebnem, Su, An-Jey A., Tannahill, Gillian M., Galson, Deborah L., O’Neill, Luke A., Auron, Philip E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731334/
https://www.ncbi.nlm.nih.gov/pubmed/23936458
http://dx.doi.org/10.1371/journal.pone.0070622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731334/
https://www.ncbi.nlm.nih.gov/pubmed/23936458
http://dx.doi.org/10.1371/journal.pone.0070622

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