Short Term Exercise Induces PGC-1α, Ameliorates Inflammation and Increases Mitochondrial Membrane Proteins but Fails to Increase Respiratory Enzymes in Aging Diabetic Hearts

PGC-1α, a transcriptional coactivator, controls inflammation and mitochondrial gene expression in insulin-sensitive tissues following exercise intervention. However, attributing such effects to PGC-1α is counfounded by exercise-induced fluctuations in blood glucose, insulin or bodyweight in diabetic...

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Detalles Bibliográficos
Autores principales: Botta, Amy, Laher, Ismail, Beam, Julianne, DeCoffe, Daniella, Brown, Kirsty, Halder, Swagata, Devlin, Angela, Gibson, Deanna L., Ghosh, Sanjoy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731348/
https://www.ncbi.nlm.nih.gov/pubmed/23936397
http://dx.doi.org/10.1371/journal.pone.0070248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731348/
https://www.ncbi.nlm.nih.gov/pubmed/23936397
http://dx.doi.org/10.1371/journal.pone.0070248

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