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Dysregulated Bile Acid Synthesis, Metabolism and Excretion in a High Fat-Cholesterol Diet-Induced Fibrotic Steatohepatitis in Rats

BACKGROUND AND AIMS: Cholesterol over-intake is involved in the onset of nonalcoholic steatohepatitis (NASH), and hepatocellular bile acid (BA) accumulation correlates with liver injuries. However, how dietary cholesterol influences cholesterol and BA kinetics in NASH liver remains ambiguous and nee...

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Detalles Bibliográficos
Autores principales: Jia, Xiaofang, Naito, Hisao, Yetti, Husna, Tamada, Hazuki, Kitamori, Kazuya, Hayashi, Yumi, Wang, Dong, Yanagiba, Yukie, Wang, Juncai, Ikeda, Katsumi, Yamori, Yukio, Nakajima, Tamie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731517/
https://www.ncbi.nlm.nih.gov/pubmed/23824403
http://dx.doi.org/10.1007/s10620-013-2747-1