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Agonistic anti-ICAM-1 antibodies in scleroderma: Activation of endothelial pro-inflammatory cascades

BACKGROUND: Scleroderma (SSc) is a complex autoimmune disorder that can be characterised by the presence 2of circulating autoantibodies to nuclear, cytoplasmic and cell surface antigens. In particular antibodies directed against endothelial cell antigens (anti-endothelial cell antibodies; AECA) have...

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Detalles Bibliográficos
Autores principales: Wolf, Sabine I., Howat, Sarah, Abraham, David J., Pearson, Jeremy D., Lawson, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731553/
https://www.ncbi.nlm.nih.gov/pubmed/23685129
http://dx.doi.org/10.1016/j.vph.2013.05.002