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Simvastatin reduces venous stenosis formation in a murine hemodialysis vascular access model

Venous neointimal hyperplasia (VNH) is responsible for hemodialysis vascular access malfunction. Here we tested whether VNH formation occurs, in part, due to vascular endothelial growth factor-A (VEGF-A) and matrix metalloproteinase (MMP)-9 gene expression causing adventitial fibroblast transdiffere...

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Detalles Bibliográficos
Autores principales: Janardhanan, Rajiv, Yang, Binxia, Vohra, Pawan, Roy, Bhaskar, Withers, Sarah, Bhattacharya, Santanu, Mandrekar, Jaywant, Kong, Hyunjoon, Leof, Edward B, Mukhopadhyay, Debabrata, Misra, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731558/
https://www.ncbi.nlm.nih.gov/pubmed/23636169
http://dx.doi.org/10.1038/ki.2013.112