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An experimental study to identify the potential role of pharmacogenomics in determining the occurrence of oxaliplatin-induced liver injury

BACKGROUND: Oxaliplatin-based chemotherapy has been linked to the development of sinusoidal obstruction syndrome (SOS), which is detrimental to outcome after liver resection for colorectal liver metastases (CLM). The aim of this study was to determine how the expression of genes involved in the tran...

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Detalles Bibliográficos
Autores principales: Robinson, Stuart M, Mann, Jelena, Manas, Derek M, Mann, Derek A, White, Steven A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731578/
https://www.ncbi.nlm.nih.gov/pubmed/23458185
http://dx.doi.org/10.1111/hpb.12010