Effect of the combination of metformin and fenofibrate on glucose homeostasis in diabetic Goto-Kakizaki rats

Metformin has been reported to increase the expression of the glucagon-like peptide-1 (GLP-1) receptor in pancreatic beta cells in a peroxisome proliferator-activated receptor (PPAR)-α-dependent manner. We investigated whether a PPARα agonist, fenofibrate, exhibits an additive or synergistic effect...

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Detalles Bibliográficos
Autores principales: Oh, Tae Jung, Shin, Ji Yon, Kang, Gyeong Hoon, Park, Kyong Soo, Cho, Young Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731660/
https://www.ncbi.nlm.nih.gov/pubmed/23827952
http://dx.doi.org/10.1038/emm.2013.58

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731660/
https://www.ncbi.nlm.nih.gov/pubmed/23827952
http://dx.doi.org/10.1038/emm.2013.58

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