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Effect of the combination of metformin and fenofibrate on glucose homeostasis in diabetic Goto-Kakizaki rats
Metformin has been reported to increase the expression of the glucagon-like peptide-1 (GLP-1) receptor in pancreatic beta cells in a peroxisome proliferator-activated receptor (PPAR)-α-dependent manner. We investigated whether a PPARα agonist, fenofibrate, exhibits an additive or synergistic effect...
Autores principales: | Oh, Tae Jung, Shin, Ji Yon, Kang, Gyeong Hoon, Park, Kyong Soo, Cho, Young Min |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731660/ https://www.ncbi.nlm.nih.gov/pubmed/23827952 http://dx.doi.org/10.1038/emm.2013.58 |
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