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Reactive oxygen species regulate context-dependent inhibition of NFAT5 target genes

The activation of nuclear factor of activated T cells 5 (NFAT5), a well-known osmoprotective factor, can be induced by isotonic stimuli, such as activated Toll-like receptors (TLRs). It is unclear, however, how NFAT5 discriminates between isotonic and hypertonic stimuli. In this study we identified...

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Detalles Bibliográficos
Autores principales: Kim, Nam-Hoon, Hong, Bong-Ki, Choi, Soo Youn, Moo Kwon, Hyug, Cho, Chul-Soo, Yi, Eugene C, Kim, Wan-Uk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731662/
https://www.ncbi.nlm.nih.gov/pubmed/23867654
http://dx.doi.org/10.1038/emm.2013.61