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Cerebrospinal Aβ11-x and 17-x levels as indicators of mild cognitive impairment and patients' stratification in Alzheimer's disease

In the present work, the concentrations of Aβ11-x and Aβ17-x peptides (x=40 or 42), which result from the combined cleavages of β-amyloid precursor protein (AβPP) by β'/α or α/γ-secretases, respectively, were assessed in cerebrospinal fluid (CSF) samples from patients with Alzheimer's dise...

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Detalles Bibliográficos
Autores principales: Abraham, J-D, Promé, S, Salvetat, N, Rubrecht, L, Cobo, S, du Paty, E, Galéa, P, Mathieu-Dupas, E, Ranaldi, S, Caillava, C, Crémer, G-A, Rieunier, F, Robert, P, Molina, F, Laune, D, Checler, F, Fareh, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731790/
https://www.ncbi.nlm.nih.gov/pubmed/23860482
http://dx.doi.org/10.1038/tp.2013.58