Interaction between the MTHFR C677T polymorphism and traumatic childhood events predicts depression

Childhood trauma is associated with the onset and recurrence of major depressive disorder (MDD). The thermolabile T variant of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism (rs1801133) is associated with a limited (oxidative) stress defense. Therefore, C677T MTHFR could be a pot...

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Detalles Bibliográficos
Autores principales: Lok, A, Bockting, C L H, Koeter, M W J, Snieder, H, Assies, J, Mocking, R J T, Vinkers, C H, Kahn, R S, Boks, M P, Schene, A H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731792/
https://www.ncbi.nlm.nih.gov/pubmed/23900311
http://dx.doi.org/10.1038/tp.2013.60

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731792/
https://www.ncbi.nlm.nih.gov/pubmed/23900311
http://dx.doi.org/10.1038/tp.2013.60

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