Adeno-associated Virus-mediated, Mifepristone-regulated Transgene Expression in the Brain

Gene therapy, in its current configuration, is irreversible and does not allow control over transgene expression in case of side effects. Only few regulated vector systems are available, and none of these has reached clinical applicability yet. The mifepristone (Mfp)-regulated Gene Switch (GS) syste...

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Detalles Bibliográficos
Autores principales: Maddalena, Andrea, Tereshchenko, Julia, Bähr, Mathias, Kügler, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Methods - Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731885/
https://www.ncbi.nlm.nih.gov/pubmed/23860550
http://dx.doi.org/10.1038/mtna.2013.35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731885/
https://www.ncbi.nlm.nih.gov/pubmed/23860550
http://dx.doi.org/10.1038/mtna.2013.35

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