Cargando…

An Algorithm for Generating Small RNAs Capable of Epigenetically Modulating Transcriptional Gene Silencing and Activation in Human Cells

Small noncoding antisense RNAs (sasRNAs) guide epigenetic silencing complexes to target loci in human cells and modulate gene transcription. When these targeted loci are situated within a promoter, long-term, stable epigenetic silencing of transcription can occur. Recent studies suggest that there e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ackley, Amanda, Lenox, Alexandra, Stapleton, Kenneth, Knowling, Stuart, Lu, Tim, Sabir, Kenny S, Vogt, Peter K, Morris, Kevin V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731886/ https://www.ncbi.nlm.nih.gov/pubmed/23839098 http://dx.doi.org/10.1038/mtna.2013.33

Ejemplares similares

Chemically Modified Oligonucleotides Modulate an Epigenetically Varied and Transient Form of Transcription Silencing of HIV-1 in Human Cells
por: Knowling, Stuart, et al.
Publicado: (2012)

An Algorithm for Generating Small RNAs Capable of Epigenetically Modulating Transcriptional Gene Silencing and Activation in Human Cells
Publicado: (2014)

Identification and Functional Analysis of Epigenetically Silenced MicroRNAs in Colorectal Cancer Cells
por: Yan, Hongli, et al.
Publicado: (2011)

Small RNA-Mediated Epigenetic Myostatin Silencing
por: Roberts, Thomas C, et al.
Publicado: (2012)

Role of microRNAs in epigenetic silencing of the CHD5 tumor suppressor gene in neuroblastomas
por: Naraparaju, Koumudi, et al.
Publicado: (2016)

RNA-directed epigenetic silencing of Periostin inhibits cell motility
por: Lister, Nicholas C., et al.
Publicado: (2015)

Nickel and Epigenetic Gene Silencing
por: Sun, Hong, et al.
Publicado: (2013)

Epigenetic silencing in transgenic plants
por: Rajeevkumar, Sarma, et al.
Publicado: (2015)

Long non-coding RNA modifies chromatin: Epigenetic silencing by long non-coding RNAs
por: Saxena, Alka, et al.
Publicado: (2011)

Bortezomib-induced miRNAs direct epigenetic silencing of locus genes and trigger apoptosis in leukemia
por: Chu, Yu-Yi, et al.
Publicado: (2017)

Epigenetic Silencing of DKK3 in Medulloblastoma
por: Valdora, Francesca, et al.
Publicado: (2013)

Durable CRISPR-Based Epigenetic Silencing
por: Nakamura, Muneaki, et al.
Publicado: (2021)

Efficient Generation of diRNAs Requires Components in the Posttranscriptional Gene Silencing Pathway
por: Miki, Daisuke, et al.
Publicado: (2017)

Epigenetic Silencing of SOX15 Is Controlled by miRNAs rather than Methylation in Papillary Thyroid Cancer
por: Ozaydin, Ahmet, et al.
Publicado: (2021)

Relating SMCHD1 structure to its function in epigenetic silencing
por: Gurzau, Alexandra D., et al.
Publicado: (2020)

Two ways of epigenetic silencing of TFPI2 in cervical cancer
por: Fullár, Alexandra, et al.
Publicado: (2020)

Telomeric Trans-Silencing: An Epigenetic Repression Combining RNA Silencing and Heterochromatin Formation
por: Josse, Thibaut, et al.
Publicado: (2007)

A Position Effect on the Heritability of Epigenetic Silencing
por: Singh, Jaswinder, et al.
Publicado: (2008)

Epigenetic silencing of TIMP4 in heart failure
por: Chaturvedi, Pankaj, et al.
Publicado: (2016)

Silencing of retroviruses by small RNAs in Drosophila
por: Brun, Christine, et al.
Publicado: (2009)

microRNAs: the art of silencing in the ear
por: Rudnicki, Anya, et al.
Publicado: (2012)

Correction: A Position Effect on the Heritability of Epigenetic Silencing
por: Singh, Jaswinder, et al.
Publicado: (2009)

RNA and epigenetic silencing: Insight from fission yeast
por: Goto, Derek B, et al.
Publicado: (2012)

Epigenetic Activation and Silencing of the Gene that Encodes IFN-γ
por: Aune, Thomas M., et al.
Publicado: (2013)

Epigenetic silencing of clustered tRNA genes in Arabidopsis
por: Hummel, Guillaume, et al.
Publicado: (2020)

Molecules of Silence: Effects of Meditation on Gene Expression and Epigenetics
por: Venditti, Sabrina, et al.
Publicado: (2020)

Epigenetic silencing of MEIS2 in prostate cancer recurrence
por: Nørgaard, Maibritt, et al.
Publicado: (2019)

Epigenetic silencing of a multifunctional plant stress regulator
por: Zander, Mark, et al.
Publicado: (2019)

Epigenetic gene silencing by heterochromatin primes fungal resistance
por: Torres-Garcia, Sito, et al.
Publicado: (2020)

Epigenetic silencing of selected hypothalamic neuropeptides in narcolepsy with cataplexy
por: Seifinejad, Ali, et al.
Publicado: (2023)

Endothelin-3 is epigenetically silenced in endometrioid endometrial cancer
por: Zmarzły, Nikola, et al.
Publicado: (2022)

Epigenetic history of an Arabidopsis trans-silencer locus and a test for relay of trans-silencing activity
por: Qin, Huaxia, et al.
Publicado: (2002)

Targeting the IGF-1R signaling and mechanisms for epigenetic gene silencing in human multiple myeloma
por: Jernberg-Wiklund, Helena, et al.
Publicado: (2012)

Non-perfectly matching small RNAs can induce stable and heritable epigenetic modifications and can be used as molecular markers to trace the origin and fate of silencing RNAs
por: Fei, Yue, et al.
Publicado: (2021)

Modulation of gene-specific epigenetic states and transcription by non-coding RNAs
por: Morris, Kevin V.
Publicado: (2011)

Conditional gene silencing of multiple genes with antisense RNAs and generation of a mutator strain of Escherichia coli
por: Nakashima, Nobutaka, et al.
Publicado: (2009)

Intron-derived small RNAs for silencing viral RNAs in mosquito cells
por: Tng, Priscilla Y. L., et al.
Publicado: (2022)

Silencing by small RNAs is linked to endosome trafficking
por: Lee, Young Sik, et al.
Publicado: (2009)

Role of DNA Methylation and Epigenetic Silencing of HAND2 in Endometrial Cancer Development
por: Jones, Allison, et al.
Publicado: (2013)

Epigenetic Silencing of Plasmodium falciparum Genes Linked to Erythrocyte Invasion
por: Cortés, Alfred, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_8jn2s2tvpvtf6al3jpthovlh7t