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TanCAR: A Novel Bispecific Chimeric Antigen Receptor for Cancer Immunotherapy

Targeted T cells are emerging as effective non-toxic therapies for cancer. Multiple elements, however, contribute to the overall pathogenesis of cancer through both distinct and redundant mechanisms. Hence, targeting multiple cancer-specific markers simultaneously could result in better therapeutic...

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Detalles Bibliográficos
Autores principales: Grada, Zakaria, Hegde, Meenakshi, Byrd, Tiara, Shaffer, Donald R, Ghazi, Alexia, Brawley, Vita S, Corder, Amanda, Schönfeld, Kurt, Koch, Joachim, Dotti, Gianpietro, Heslop, Helen E, Gottschalk, Stephen, Wels, Winfried S, Baker, Matthew L, Ahmed, Nabil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731887/
https://www.ncbi.nlm.nih.gov/pubmed/23839099
http://dx.doi.org/10.1038/mtna.2013.32