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Intraspinal AAV Injections Immediately Rostral to a Thoracic Spinal Cord Injury Site Efficiently Transduces Neurons in Spinal Cord and Brain

In the vast majority of studies utilizing adeno-associated virus (AAV) in central nervous system applications, including those published with spinal cord injury (SCI) models, AAV has been administered at the level of the cell body of neurons targeted for genetic modification, resulting in transducti...

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Detalles Bibliográficos
Autores principales: Klaw, Michelle C, Xu, Chen, Tom, Veronica J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731889/
https://www.ncbi.nlm.nih.gov/pubmed/23881451
http://dx.doi.org/10.1038/mtna.2013.34