Cargando…
Ethers and esters derived from apocynin avoid the interaction between p47phox and p22phox subunits of NADPH oxidase: evaluation in vitro and in silico
NOX (NADPH oxidase) plays an important role during several pathologies because it produces the superoxide anion (O(2)(•−)), which reacts with NO (nitric oxide), diminishing its vasodilator effect. Although different isoforms of NOX are expressed in ECs (endothelial cells) of blood vessels, the NOX2...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731894/ https://www.ncbi.nlm.nih.gov/pubmed/23802190 http://dx.doi.org/10.1042/BSR20130029 |