Cargando…

Ethers and esters derived from apocynin avoid the interaction between p47phox and p22phox subunits of NADPH oxidase: evaluation in vitro and in silico

NOX (NADPH oxidase) plays an important role during several pathologies because it produces the superoxide anion (O(2)(•−)), which reacts with NO (nitric oxide), diminishing its vasodilator effect. Although different isoforms of NOX are expressed in ECs (endothelial cells) of blood vessels, the NOX2...

Descripción completa

Detalles Bibliográficos
Autores principales:	Macías-Pérez, Martha Edith, Martínez-Ramos, Federico, Padilla-Martínez, Itzia Irene, Correa-Basurto, José, Kispert, Lowell, Mendieta-Wejebe, Jessica Elena, Rosales-Hernández, Martha Cecilia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2013
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731894/ https://www.ncbi.nlm.nih.gov/pubmed/23802190 http://dx.doi.org/10.1042/BSR20130029

Ejemplares similares

ROCK2 interacts with p22phox to phosphorylate p47phox and to control NADPH oxidase activation in human monocytes
por: Tlili, Asma, et al.
Publicado: (2023)

HSCARG Inhibits NADPH Oxidase Activity through Regulation of the Expression of p47phox
por: Xiao, Weichun, et al.
Publicado: (2013)

New NADPH Oxidase 2 Inhibitors Display Potent Activity against Oxidative Stress by Targeting p22(phox)-p47(phox) Interactions
por: Treuer, Adriana V., et al.
Publicado: (2023)

156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox
Publicado: (1994)

Pioglitazone Inhibits the Expressions of p22(phox) and p47(phox) in Rat Mesangial Cells In Vitro
por: Wang, Shan, et al.
Publicado: (2014)

Exercise Training Attenuates Upregulation of p47(phox) and p67(phox) in Hearts of Diabetic Rats
por: Sharma, Neeru M., et al.
Publicado: (2016)

Molecular Insights of p47(phox) Phosphorylation Dynamics in the Regulation of NADPH Oxidase Activation and Superoxide Production
por: Meijles, Daniel N., et al.
Publicado: (2014)

Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils
por: Ohayon, Delphine, et al.
Publicado: (2019)

oxLDL-mediated cellular senescence is associated with increased NADPH oxidase p47phox recruitment to caveolae
por: Wang, Jing, et al.
Publicado: (2018)

Correction: Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils
por: Ohayon, Delphine, et al.
Publicado: (2019)

Subcellular localisation of the p40(phox) component of NADPH oxidase involves direct interactions between the Phox homology domain and F-actin
por: Shao, Dongmin, et al.
Publicado: (2010)

Involvement of p40phox in activation of phagocyte NADPH oxidase through association of its carboxyl-terminal, but not its amino-terminal, with p67phox
Publicado: (1996)

Chemical synthesis of a reported p47phox/p22phox inhibitor and characterization of its instability and irreproducible activity
por: Zang, Jie, et al.
Publicado: (2023)

NADPH oxidase p47phox siRNA attenuates adventitial fibroblasts proliferation and migration in apoE(-/-) mouse
por: Xu, Fang, et al.
Publicado: (2015)

Colitis susceptibility in p47(phox−/−) mice is mediated by the microbiome
por: Falcone, E. Liana, et al.
Publicado: (2016)

p47phox contributes to albuminuria and kidney fibrosis in mice
por: Wang, Hongtao, et al.
Publicado: (2015)

Postsynaptic p47phox regulates long-term depression in the hippocampus
por: Yi, Jee Hyun, et al.
Publicado: (2018)

The NADPH organizers NoxO1 and p47phox are both mediators of diabetes-induced vascular dysfunction in mice
por: Rezende, Flávia, et al.
Publicado: (2017)

The Modulation of NADPH Oxidase Activity in Human Neutrophils by Moroccan Strains of Leishmania major and Leishmania tropica Is Not Associated with p47(phox) Phosphorylation
por: Maksouri, Hasnaa, et al.
Publicado: (2021)

Gene transfer and expression in human neutrophils. The phox homology domain of p47(phox )translocates to the plasma membrane but not to the membrane of mature phagosomes
por: Johnson, Jennifer L, et al.
Publicado: (2006)

Molecular evolution of Phox-related regulatory subunits for NADPH oxidase enzymes
por: Kawahara, Tsukasa, et al.
Publicado: (2007)

The p47phox mouse knock-out model of chronic granulomatous disease
Publicado: (1995)

Phosphorylation of threonine 154 in p40(phox) is an important physiological signal for activation of the neutrophil NADPH oxidase
por: Chessa, Tamara A. M., et al.
Publicado: (2010)

Regulation of Derlin-1-mediated degradation of NADPH oxidase partner p22(phox) by thiol modification
por: Miyano, Kei, et al.
Publicado: (2022)

Novel PKC-ζ to p47(phox) interaction is necessary for transformation from blebbishields
por: Jinesh, Goodwin G., et al.
Publicado: (2016)

NADPH Oxidase p22(phox) C242T Polymorphism and Ischemic Cerebrovascular Disease: An Updated Meta-Analysis
por: Li, Pingping, et al.
Publicado: (2015)

Apocynin prevents mitochondrial burdens, microglial activation, and pro-apoptosis induced by a toxic dose of methamphetamine in the striatum of mice via inhibition of p47phox activation by ERK
por: Dang, Duy-Khanh, et al.
Publicado: (2016)

The gp91(phox) Component of NADPH Oxidase Is Not a Voltage-gated Proton Channel
por: DeCoursey, Thomas E., et al.
Publicado: (2002)

Myricitrin Modulates NADPH Oxidase-Dependent ROS Production to Inhibit Endotoxin-Mediated Inflammation by Blocking the JAK/STAT1 and NOX2/p47(phox) Pathways
por: Qi, Shimei, et al.
Publicado: (2017)

Angiopoietin-1 Requires Oxidant Signaling through p47phox to Promote Endothelial Barrier Defense
por: Ghosh, Chandra C., et al.
Publicado: (2015)

Novel Diagnostic Tool for p47(phox)-Deficient Chronic Granulomatous Disease Patient and Carrier Detection
por: Wrona, Dominik, et al.
Publicado: (2019)

p47(phox) deficiency improves cognitive impairment and attenuates tau hyperphosphorylation in mouse models of AD
por: Gong, Ping, et al.
Publicado: (2020)

p47phox deficiency impairs platelet function and protects mice against arterial and venous thrombosis
por: Wang, Xiamin, et al.
Publicado: (2020)

Lipoxin A4 attenuates uric acid-activated, NADPH oxidase-dependent oxidative stress by interfering with translocation of p47phox in human umbilical vein endothelial cells
por: Zhou, You, et al.
Publicado: (2020)

Neutrophils from p40(phox−/−) mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing
por: Ellson, Chris D., et al.
Publicado: (2006)

The phosphoinositide-binding protein p40(phox) activates the NADPH oxidase during FcγIIA receptor–induced phagocytosis
por: Suh, Chang-Il, et al.
Publicado: (2006)

Association between NADPH Oxidase p22(phox) C242T Polymorphism and Ischemic Cerebrovascular Disease: A Meta-Analysis
por: Li, Bing-Hu, et al.
Publicado: (2013)

Administration of losartan preserves cardiomyocyte size and prevents myocardial dysfunction in tail-suspended mice by inhibiting p47(phox) phosphorylation, NADPH oxidase activation and MuRF1 expression
por: Liang, Liwen, et al.
Publicado: (2019)

NADPH oxidase gp91(phox) contributes to RANKL-induced osteoclast differentiation by upregulating NFATc1
por: Kang, In Soon, et al.
Publicado: (2016)

P47(phox−/−) Mice Are Compromised in Expansion and Activation of CD8(+) T Cells and Susceptible to Trypanosoma cruzi Infection
por: Dhiman, Monisha, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_bot5neiodpr9887cbs1qdp3t14