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Do Natural T Regulatory Cells become Activated to Antigen Specific T Regulatory Cells in Transplantation and in Autoimmunity?
Antigen specific T regulatory cells (T(reg)) are often CD4(+)CD25(+)FoxP3(+) T cells, with a phenotype similar to natural T(reg) (nT(reg)). It is assumed that nT(reg) cannot develop into an antigen specific T(reg) as repeated culture with IL-2 and a specific antigen does not increase the capacity or...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731939/ https://www.ncbi.nlm.nih.gov/pubmed/23935597 http://dx.doi.org/10.3389/fimmu.2013.00208 |