Do Natural T Regulatory Cells become Activated to Antigen Specific T Regulatory Cells in Transplantation and in Autoimmunity?

Antigen specific T regulatory cells (T(reg)) are often CD4(+)CD25(+)FoxP3(+) T cells, with a phenotype similar to natural T(reg) (nT(reg)). It is assumed that nT(reg) cannot develop into an antigen specific T(reg) as repeated culture with IL-2 and a specific antigen does not increase the capacity or...

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Detalles Bibliográficos
Autores principales: Hall, Bruce M., Tran, Giang T., Verma, Nirupama D., Plain, Karren M., Robinson, Catherine M., Nomura, Masaru, Hodgkinson, Suzanne J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731939/
https://www.ncbi.nlm.nih.gov/pubmed/23935597
http://dx.doi.org/10.3389/fimmu.2013.00208

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