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Modeling the evolution dynamics of exon-intron structure with a general random fragmentation process
BACKGROUND: Most eukaryotic genes are interrupted by spliceosomal introns. The evolution of exon-intron structure remains mysterious despite rapid advance in genome sequencing technique. In this work, a novel approach is taken based on the assumptions that the evolution of exon-intron structure is a...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732091/ https://www.ncbi.nlm.nih.gov/pubmed/23448166 http://dx.doi.org/10.1186/1471-2148-13-57 |