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Induction of TGF-β1 Synthesis by Macrophages in Response to Apoptotic Cells Requires Activation of the Scavenger Receptor CD36

BACKGROUND/OBJECTIVE: Phosphatidylserine (PS) exposed on apoptotic cells has been shown to stimulate production of transforming growth factor-β (TGF-β) and promote anti-inflammatory responses. However, the PS receptor(s) responsible for this induction has not been clearly determined. METHODOLOGY/PRI...

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Detalles Bibliográficos
Autores principales: Xiong, Weipeng, Frasch, S. Courtney, Thomas, Stacey M., Bratton, Donna L., Henson, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732218/
https://www.ncbi.nlm.nih.gov/pubmed/23936544
http://dx.doi.org/10.1371/journal.pone.0072772