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Lyn Facilitates Glioblastoma Cell Survival under Conditions of Nutrient Deprivation by Promoting Autophagy

Members of the Src family kinases (SFK) can modulate diverse cellular processes, including division, death and survival, but their role in autophagy has been minimally explored. Here, we investigated the roles of Lyn, a SFK, in promoting the survival of human glioblastoma tumor (GBM) cells in vitro...

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Detalles Bibliográficos
Autores principales: Liu, Wei Michael, Huang, Ping, Kar, Niladri, Burgett, Monica, Muller-Greven, Gaelle, Nowacki, Amy S., Distelhorst, Clark W., Lathia, Justin D., Rich, Jeremy N., Kappes, John C., Gladson, Candece L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732228/
https://www.ncbi.nlm.nih.gov/pubmed/23936469
http://dx.doi.org/10.1371/journal.pone.0070804