Cargando…

LT-IIb(T13I), a Non-Toxic Type II Heat-Labile Enterotoxin, Augments the Capacity of a Ricin Toxin Subunit Vaccine to Evoke Neutralizing Antibodies and Protective Immunity

Currently, there is a shortage of adjuvants that can be employed with protein subunit vaccines to enhance protection against biological threats. LT-IIb(T13I) is an engineered nontoxic derivative of LT-IIb, a member of the type II subfamily of heat labile enterotoxins expressed by Escherichia coli, t...

Descripción completa

Detalles Bibliográficos
Autores principales: Greene, Christopher J., Chadwick, Chrystal M., Mandell, Lorrie M., Hu, John C., O’Hara, Joanne M., Brey, Robert N., Mantis, Nicholas J., Connell, Terry D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732243/
https://www.ncbi.nlm.nih.gov/pubmed/23936344
http://dx.doi.org/10.1371/journal.pone.0069678