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Laulimalide Induces Dose-Dependent Modulation of Microtubule Behaviour in the C. elegans Embryo

Laulimalide is a microtubule-binding drug that was originally isolated from marine sponges. High concentrations of laulimalide stabilize microtubules and inhibit cell division similarly to paclitaxel; however, there are important differences with respect to the nature of the specific cellular defect...

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Detalles Bibliográficos
Autores principales: Bajaj, Megha, Srayko, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732258/
https://www.ncbi.nlm.nih.gov/pubmed/23936530
http://dx.doi.org/10.1371/journal.pone.0071889