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20-HETE and EETs in Diabetic Nephropathy: A Novel Mechanistic Pathway

Diabetic nephropathy (DN), a major complication of diabetes, is characterized by hypertrophy, extracellular matrix accumulation, fibrosis and proteinuria leading to loss of renal function. Hypertrophy is a major factor inducing proximal tubular epithelial cells injury. However, the mechanisms leadin...

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Detalles Bibliográficos
Autores principales: Eid, Stephanie, Maalouf, Rita, Jaffa, Ayad A., Nassif, Joseph, Hamdy, Ahmed, Rashid, Awad, Ziyadeh, Fuad N., Eid, Assaad A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732284/
https://www.ncbi.nlm.nih.gov/pubmed/23936373
http://dx.doi.org/10.1371/journal.pone.0070029