GPR88 Reveals a Discrete Function of Primary Cilia as Selective Insulators of GPCR Cross-Talk

A number of G protein-coupled receptors (GPCRs) localize to primary cilia but the functional significance of cilia to GPCR signaling remains incompletely understood. We investigated this question by focusing on the D1 dopamine receptor (D1R) and beta-2 adrenergic receptor (B2AR), closely related cat...

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Detalles Bibliográficos
Autores principales: Marley, Aaron, Choy, Regina Wai-Yan, von Zastrow, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732291/
https://www.ncbi.nlm.nih.gov/pubmed/23936473
http://dx.doi.org/10.1371/journal.pone.0070857

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732291/
https://www.ncbi.nlm.nih.gov/pubmed/23936473
http://dx.doi.org/10.1371/journal.pone.0070857

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