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GPR88 Reveals a Discrete Function of Primary Cilia as Selective Insulators of GPCR Cross-Talk
A number of G protein-coupled receptors (GPCRs) localize to primary cilia but the functional significance of cilia to GPCR signaling remains incompletely understood. We investigated this question by focusing on the D1 dopamine receptor (D1R) and beta-2 adrenergic receptor (B2AR), closely related cat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732291/ https://www.ncbi.nlm.nih.gov/pubmed/23936473 http://dx.doi.org/10.1371/journal.pone.0070857 |