ATM-deficient human neural stem cells as an in vitro model system to study neurodegeneration

Loss of ATM kinase, a transducer of the DNA damage response and redox sensor, causes the neurodegenerative disorder ataxia-telangiectasia (A-T). While a great deal of progress has been made in elucidating the ATM-dependent DNA damage response (DDR) network, a key challenge remains in understanding t...

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Detalles Bibliográficos
Autores principales: Carlessi, Luigi, Fusar Poli, Elena, De Filippis, Lidia, Delia, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732388/
https://www.ncbi.nlm.nih.gov/pubmed/23707302
http://dx.doi.org/10.1016/j.dnarep.2013.04.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732388/
https://www.ncbi.nlm.nih.gov/pubmed/23707302
http://dx.doi.org/10.1016/j.dnarep.2013.04.013

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