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ATM-deficient human neural stem cells as an in vitro model system to study neurodegeneration
Loss of ATM kinase, a transducer of the DNA damage response and redox sensor, causes the neurodegenerative disorder ataxia-telangiectasia (A-T). While a great deal of progress has been made in elucidating the ATM-dependent DNA damage response (DDR) network, a key challenge remains in understanding t...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732388/ https://www.ncbi.nlm.nih.gov/pubmed/23707302 http://dx.doi.org/10.1016/j.dnarep.2013.04.013 |