Deubiquitinases Sharpen Substrate Discrimination during Membrane Protein Degradation from the ER

Newly synthesized membrane proteins are queried by ubiquitin ligase complexes and triaged between degradative and nondegradative fates. The mechanisms that convert modest differences in substrate-ligase interactions into decisive outcomes of ubiquitination are not well understood. Here, we reconstit...

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Detalles Bibliográficos
Autores principales: Zhang, Zai-Rong, Bonifacino, Juan S., Hegde, Ramanujan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732389/
https://www.ncbi.nlm.nih.gov/pubmed/23890821
http://dx.doi.org/10.1016/j.cell.2013.06.038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732389/
https://www.ncbi.nlm.nih.gov/pubmed/23890821
http://dx.doi.org/10.1016/j.cell.2013.06.038

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