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Molecular dynamics simulation of complex Histones Deacetylase (HDAC) Class II Homo Sapiens with suberoylanilide hydroxamic acid (SAHA) and its derivatives as inhibitors of cervical cancer

Cervical cancer is second most common cancer in woman worldwide. Cervical cancer caused by human papillomavirus (HPV) oncogene. Inhibition of histone deacetylase (HDAC) activity has been known as a potential strategy for cancer therapy. SAHA is an HDAC inhibitor that has been used in cancer therapy...

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Detalles Bibliográficos
Autores principales: Tambunan, Usman Sumo Friend, Bakri, Ridla, Prasetia, Tirtana, Parikesit, Arli Aditya, Kerami, Djati
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732443/
https://www.ncbi.nlm.nih.gov/pubmed/23930022
http://dx.doi.org/10.6026/97320630009696