LANDSCAPE OF THE MITOCHONDRIAL Hsp90 METABOLOME IN TUMORS

Reprogramming of tumor cell metabolism contributes to disease progression and resistance to therapy, but how this process is regulated on the molecular level is unclear. Here we report that Heat Shock Protein 90 (Hsp90)-directed protein folding in mitochondria controls central metabolic networks in...

Descripción completa

Detalles Bibliográficos
Autores principales: Chae, Young Chan, Angelin, Alessia, Lisanti, Sofia, Kossenkov, Andrew A., Speicher, Kaye D., Wang, Huan, Powers, James F., Tischler, Arthur S., Pacak, Karel, Fliedner, Stephanie, Michalek, Ryan D., Karoly, Edward D., Wallace, Douglas C., Languino, Lucia R., Speicher, David W., Altieri, Dario C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732457/
https://www.ncbi.nlm.nih.gov/pubmed/23842546
http://dx.doi.org/10.1038/ncomms3139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732457/
https://www.ncbi.nlm.nih.gov/pubmed/23842546
http://dx.doi.org/10.1038/ncomms3139

Ejemplares similares