Unusual base pairing during the decoding of a stop codon by the ribosome

During normal translation, binding of a release factor to one of the three stop codons (UGA, UAA or UAG) results in termination of protein synthesis. However, modification of the initial uridine to a pseudouridine (Ψ) allows efficient recognition and read-through of these stop codons by a transfer R...

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Detalles Bibliográficos
Autores principales: Fernández, Israel S., Ng, Chyan Leong, Kelley, Ann C., Wu, Guowei, Yu, Yi-Tao, Ramakrishnan, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732562/
https://www.ncbi.nlm.nih.gov/pubmed/23812587
http://dx.doi.org/10.1038/nature12302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732562/
https://www.ncbi.nlm.nih.gov/pubmed/23812587
http://dx.doi.org/10.1038/nature12302

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