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A Comparison between Use of Spray and Freeze Drying Techniques for Preparation of Solid Self-Microemulsifying Formulation of Valsartan and In Vitro and In Vivo Evaluation

The objective of the present study was to develop self micro emulsifying formulation (SMEF) of valsartan to improve its oral bioavailability. The formulations were screened on the basis of solubility, stability, emulsification efficiency, particle size and zeta potential. The optimized liquid SMEF c...

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Detalles Bibliográficos
Autores principales: Singh, Sanjay Kumar, Vuddanda, Parameswara Rao, Singh, Sanjay, Srivastava, Anand Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732638/
https://www.ncbi.nlm.nih.gov/pubmed/23971048
http://dx.doi.org/10.1155/2013/909045