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A Comparison between Use of Spray and Freeze Drying Techniques for Preparation of Solid Self-Microemulsifying Formulation of Valsartan and In Vitro and In Vivo Evaluation
The objective of the present study was to develop self micro emulsifying formulation (SMEF) of valsartan to improve its oral bioavailability. The formulations were screened on the basis of solubility, stability, emulsification efficiency, particle size and zeta potential. The optimized liquid SMEF c...
Autores principales: | Singh, Sanjay Kumar, Vuddanda, Parameswara Rao, Singh, Sanjay, Srivastava, Anand Kumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732638/ https://www.ncbi.nlm.nih.gov/pubmed/23971048 http://dx.doi.org/10.1155/2013/909045 |
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