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Beyond the Antigen Receptor: Editing the Genome of T-Cells for Cancer Adoptive Cellular Therapies

Recent early stage clinical trials evaluating the adoptive transfer of patient CD8(+) T-cells re-directed with antigen receptors recognizing tumors have shown very encouraging results. These reports provide strong support for further development of the therapeutic concept as a curative cancer treatm...

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Detalles Bibliográficos
Autores principales: Lloyd, Angharad, Vickery, Owen N., Laugel, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733021/
https://www.ncbi.nlm.nih.gov/pubmed/23935598
http://dx.doi.org/10.3389/fimmu.2013.00221