Human DNA Glycosylase NEIL1’s Interactions with Downstream Repair Proteins Is Critical for Efficient Repair of Oxidized DNA Base Damage and Enhanced Cell Survival

NEIL1 is unique among the oxidatively damaged base repair-initiating DNA glycosylases in the human genome due to its S phase-specific activation and ability to excise substrate base lesions from single-stranded DNA. We recently characterized NEIL1’s specific binding to downstream canonical repair an...

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Detalles Bibliográficos
Autores principales: Hegde, Muralidhar L., Hegde, Pavana M., Arijit, Dutta, Boldogh, Istvan, Mitra, Sankar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733129/
https://www.ncbi.nlm.nih.gov/pubmed/23926464
http://dx.doi.org/10.3390/biom2040564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733129/
https://www.ncbi.nlm.nih.gov/pubmed/23926464
http://dx.doi.org/10.3390/biom2040564

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