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On the assessment of the added value of new predictive biomarkers

BACKGROUND: The surge in biomarker development calls for research on statistical evaluation methodology to rigorously assess emerging biomarkers and classification models. Recently, several authors reported the puzzling observation that, in assessing the added value of new biomarkers to existing one...

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Detalles Bibliográficos
Autores principales: Chen, Weijie, Samuelson, Frank W, Gallas, Brandon D, Kang, Le, Sahiner, Berkman, Petrick, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733611/
https://www.ncbi.nlm.nih.gov/pubmed/23895587
http://dx.doi.org/10.1186/1471-2288-13-98