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A network model of genomic hormone interactions underlying dementia and its translational validation through serendipitous off-target effect

BACKGROUND: While the majority of studies have focused on the association between sex hormones and dementia, emerging evidence supports the role of other hormone signals in increasing dementia risk. However, due to the lack of an integrated view on mechanistic interactions of hormone signaling pathw...

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Detalles Bibliográficos
Autores principales: Younesi, Erfan, Hofmann-Apitius, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733613/
https://www.ncbi.nlm.nih.gov/pubmed/23885764
http://dx.doi.org/10.1186/1479-5876-11-177