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The Synergistic Immunoregulatory Effects of Culture-Expanded Mesenchymal Stromal Cells and CD4(+)25(+)Foxp3(+) Regulatory T Cells on Skin Allograft Rejection
Mesenchymal stromal cells (MSCs) are seen as an ideal source of cells to induce graft acceptance; however, some reports have shown that MSCs can be immunogenic rather than immunosuppressive. We speculate that the immunomodulatory effects of regulatory T cells (Tregs) can aid the maintenance of immun...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733648/ https://www.ncbi.nlm.nih.gov/pubmed/23940676 http://dx.doi.org/10.1371/journal.pone.0070968 |