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NMDA receptor subunits have different roles in NMDA-induced neurotoxicity in the retina

BACKGROUND: Loss of retinal ganglion cells (RGCs) is a hallmark of various retinal diseases including glaucoma, retinal ischemia, and diabetic retinopathy. N-methyl-D-aspartate (NMDA)-type glutamate receptor (NMDAR)-mediated excitotoxicity is thought to be an important contributor to RGC death in th...

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Detalles Bibliográficos
Autores principales: Bai, Ning, Aida, Tomomi, Yanagisawa, Michiko, Katou, Sayaka, Sakimura, Kenji, Mishina, Masayoshi, Tanaka, Kohichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733768/
https://www.ncbi.nlm.nih.gov/pubmed/23902942
http://dx.doi.org/10.1186/1756-6606-6-34