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Exposure of Clinical MRSA Heterogeneous Strains to β-Lactams Redirects Metabolism to Optimize Energy Production through the TCA Cycle

Methicillin-resistant Staphylococcus aureus (MRSA) has emerged as one of the most important pathogens both in health care and community-onset infections. The prerequisite for methicillin resistance is mecA, which encodes a β-lactam-insensitive penicillin binding protein PBP2a. A characteristic of MR...

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Detalles Bibliográficos
Autores principales: Keaton, Mignon A., Rosato, Roberto R., Plata, Konrad B., Singh, Christopher R., Rosato, Adriana E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733780/
https://www.ncbi.nlm.nih.gov/pubmed/23940684
http://dx.doi.org/10.1371/journal.pone.0071025