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Functional Analysis of Tcl1 Using Tcl1-Deficient Mouse Embryonic Stem Cells

Tcl1 is highly expressed in embryonic stem (ES) cells, but its expression rapidly decreases following differentiation. To assess Tcl1’s roles in ES cells, we generated Tcl1-deficient and -overexpressing mouse ES cell lines. We found that Tcl1 was neither essential nor sufficient for maintaining the...

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Detalles Bibliográficos
Autores principales: Miyazaki, Tatsushi, Miyazaki, Satsuki, Ashida, Masafumi, Tanaka, Tomofumi, Tashiro, Fumi, Miyazaki, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733782/
https://www.ncbi.nlm.nih.gov/pubmed/23940776
http://dx.doi.org/10.1371/journal.pone.0071645