Microglial P2Y(12) Deficiency/Inhibition Protects against Brain Ischemia

OBJECTIVE: Microglia are among the first immune cells to respond to ischemic insults. Triggering of this inflammatory response may involve the microglial purinergic GPCR, P2Y(12), activation via extracellular release of nucleotides from injured cells. It is also the inhibitory target of the widely u...

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Detalles Bibliográficos
Autores principales: Webster, Corey M., Hokari, Masaaki, McManus, April, Tang, Xian Nan, Ma, Hualong, Kacimi, Rachid, Yenari, Midori A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733797/
https://www.ncbi.nlm.nih.gov/pubmed/23940669
http://dx.doi.org/10.1371/journal.pone.0070927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3733797/
https://www.ncbi.nlm.nih.gov/pubmed/23940669
http://dx.doi.org/10.1371/journal.pone.0070927

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